...with his dating a woman
whose most SIGNIFICANT achievement...
The Big Bang Theory Season 3, Episode 11
This is a natural human process
and we're talking about SIGNIFICANT savings.
The Big Bang Theory Season 1, Episode 4
I brought SIGNIFICANT assets
into the relationship too.
The Big Bang Theory Season 8, Episode 6
Twenty thousand data runs
and no statistically SIGNIFICANT results.
The Big Bang Theory Season 2, Episode 13
But there's been
a SIGNIFICANT reduction
in the tumors.
Breaking Bad Season 2, Episode 10