![...with his dating a woman
whose most significant achievement...
...with his dating a woman
whose most significant achievement...](data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=)
...with his dating a woman
whose most SIGNIFICANT achievement...
The Big Bang Theory Season 3, Episode 11
![This is a natural human process
and we're talking about significant savings.
This is a natural human process
and we're talking about significant savings.](data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=)
This is a natural human process
and we're talking about SIGNIFICANT savings.
The Big Bang Theory Season 1, Episode 4
![I brought significant assets
into the relationship too.
I brought significant assets
into the relationship too.](data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=)
I brought SIGNIFICANT assets
into the relationship too.
The Big Bang Theory Season 8, Episode 6
![Twenty thousand data runs
and no statistically significant results.
Twenty thousand data runs
and no statistically significant results.](data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=)
Twenty thousand data runs
and no statistically SIGNIFICANT results.
The Big Bang Theory Season 2, Episode 13
![But there's been
a significant reduction
in the tumors.
But there's been
a significant reduction
in the tumors.](data:image/png;base64,R0lGODlhAQABAAD/ACwAAAAAAQABAAACADs=)
But there's been
a SIGNIFICANT reduction
in the tumors.
Breaking Bad Season 2, Episode 10